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Compartment syndrome (increased pressure inside muscles)

Occurs in the extremities, with the lower leg being the most common site. Swelling in an enclosed space of a limb (called a compartment) causes increased pressure and decreased blood flow leading to damage to the tissues. This can result in the death of muscles and nerves. If left untreated, complete paralysis of the affected limb and/or gangrene can develop requiring amputation.

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