IndicationsThe combination of amoxicillin and clavulanic acid is used to treat certain infections caused by bacteria, including infections of the ears, lungs, sinus, skin, and urinary tract. Amoxicillin is in a class of medications called penicillin-like antibiotics. It works by stopping the growth of bacteria. Clavulanic acid is in a class of medications called beta-lactamase inhibitors. It works by preventing bacteria from destroying amoxicillin. Antibiotics will not work for colds, flu, or other viral infections.
DoseringThe combination of amoxicillin and clavulanic acid comes as a tablet, a chewable tablet, and a suspension (liquid) to take by mouth. It is usually taken with a meal or a snack every 8 hours (three times a day) or every 12 hours (twice a day). To help you remember to take amoxicillin and clavulanate, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take amoxicillin and clavulanic acid exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Shake the liquid well before each use to mix the medication evenly. The chewable tablets should be chewed thoroughly before they are swallowed. The other tablets should be taken with a full glass of water. The 250 mg and 500 mg tablets of amoxicillin and clavulanic acid contain the same amount of clavulanic acid. Do not substitute two 250 mg tablets for one 500 mg tablet. The 250 mg regular tablet and the 250 mg chewable tablet contain different amounts of clavulanic acid. They also should not be substituted. Take amoxicillin and clavulanic acid until you finish the prescription, even if you feel better. Stopping amoxicillin and clavulanic acid too soon may cause bacteria to become resistant to antibiotics.
VoorzichtigBefore taking amoxicillin and clavulanic acid, tell your doctor and pharmacist if you are allergic to amoxicillin (Amoxil, Trimox, Wymox), clavulanic acid, penicillin, cephalosporins, or any other medications. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention either of the following: allopurinol (Lopurin, Zyloprim) and probenecid (Benemid). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have or have ever had kidney or liver disease, allergies, asthma, hay fever, hives, or mononucleosis.
Amoxicillin and clavulanic acid may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- upset stomach
- mild skin rash
If you experience any of the following symptoms, call your doctor immediately:
- severe skin rash
- difficulty breathing or swallowing
- vaginal itching and discharge
- yellowing of the skin or eyes
Amoxicillin and clavulanic acid may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch
] or by phone [1-800-332-1088].