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Steven Johnson syndrome (rare, serious skin disorder)

A life-threatening allergic reaction involving a rash with skin breakdown. Steven Johnson syndrome involves very serious inflammation of the skin and mucous membranes and requires aggressive treatment and hospitalization. The skin becomes red, and blisters and sloughs after dying. Steven-Johnson is an extension of a rash known as erythema multiforme. The disorder is usually an allergic reaction to medications or infections. The most common medications involved are sulfa drugs, tetracycline, amoxicillin, ampicillin, anti-seizure medications, nonsteroidal anti-inflammatory drugs/NSAIDs (ibuprofen, naproxen) and allopurinol.

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