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Vascular insufficiency due to peripheral artery disease (PAD, claudication, inadequate blood flow)

The sensation of muscle fatigue or cramp-like pain that may occur in one or both legs, usually after minimal exercise. Symptoms are relieved after resting, and the calf is most commonly affected, but symptoms may be felt in the thighs, buttocks, hips or feet. Peripheral arterial disease from a buildup of plaque in the walls of arteries (atherosclerosis) is the usual cause. As the buildup continues the artery becomes more and more narrow, and can eventually lead to increased infections and loss of the leg.
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