Insomnia

💊 Behandelingen bij insomnia

Gerangschikt op onderbouwing (aantal onafhankelijke bronnen) en gerapporteerde frequentie.

+ Vrij verkrijgbaar bij ons

• +Diphenhydramine Hydrochloride3 bronnen🟢Nustasium Comp 20€ 14,90
  About the substance

  First-generation H1-receptor antagonist from the ethanolamine series that competitively blocks histamine H1-receptors in both the periphery and the central nervous system.

  Dosage: Apply only small amounts to the irritated skin using a gentle massage; use for a maximum of 7 days without medical advice.
• +Diphenhydramine3 bronnen🟢Nustasium Comp 20€ 14,90
  About the substance

  First-generation H1-receptor antagonist from the ethanolamine series that competitively blocks histamine H1-receptors in both the periphery and the central nervous system.

  Dosage: Apply only small amounts to the irritated skin using a gentle massage; use for a maximum of 7 days without medical advice.

+ Enkel op voorschrift — bespreek met je arts

• +Doxepin5 bronnenop voorschrift — vraag je arts
  About the substance

  Psychotropic agent, closely related to tricyclic antidepressants, with antidepressant, anxiolytic, and sedative properties.

  Dosage: Topical cream: Apply 4 times daily with at least 3-4 hours between applications, for a maximum of 8 days.
• +Doxylamine Succinate3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Doxylamine is a histamine H1-antagonist with pronounced sedative properties. By blocking H1-receptors in the central nervous system and through anticholinergic effects, it influences the sleep-wake cycle and reduces nausea.

  Dosage: For insomnia: 30 minutes before bedtime. For cold symptoms: every 4 to 6 hours. Strictly follow the label or doctor's prescription.
• +Butabarbital3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Butabarbital is a barbiturate that suppresses central nervous system activity. It enhances the effect of GABA by binding to specific receptors, leading to an extension of the opening time of chloride channels in neurons. This results in strong inhibition of neuronal excitability, which induces sedation and sleep.
• +Trazodone3 bronnenop voorschrift — vraag je arts
  About the substance

  Trazodone is an antidepressant from the SARI class (serotonin antagonist and reuptake inhibitor) that inhibits serotonin reuptake and blocks postsynaptic 5HT2A receptors.

  Dosage: Starting dose 150 mg per day, in divided doses after meals or as a single dose before bedtime; increase by 50 mg every 3-4 days up to a maximum of 400 mg per day.
• +Mirtazapine3 bronnenop voorschrift — vraag je arts
  About the substance

  Tetracyclic antidepressant that acts as an antagonist at central presynaptic α2-receptors, increasing noradrenergic and serotonergic neurotransmission, combined with blockade of 5-HT2 and 5-HT3 receptors.

  Dosage: 15 to 45 mg per day, to be taken once daily before bedtime.
• +Gamma-aminobutyric2 bronnenop voorschrift — vraag je arts
  About the substance

  GABA is the primary inhibitory neurotransmitter in the human nervous system. It binds to specific GABA receptors on nerve cells, leading to increased permeability to chloride ions and hyperpolarization of the cell membrane. This inhibits the transmission of nerve impulses, which has a calming effect on the nervous system.

  Dosage: The dosage varies greatly per product; consult the label for the recommended daily amount.
• +Phenobarbital3 bronnenop voorschrift — vraag je arts
  About the substance

  Barbiturate that acts as a non-selective central nervous system depressant. It works by binding to GABA receptors, keeping chloride ion channels open longer, which leads to hyperpolarization of the neuronal membrane and inhibition of nerve impulses.

  Dosage: Starting dose 2-3 mg/kg/day; usual maintenance dose 100-200 mg/day, to be taken as a single evening dose or divided into two doses.
• +Levomepromazine2 bronnenop voorschrift — vraag je arts
  About the substance

  Levomepromazine is an aliphatic phenothiazine antipsychotic that works by blocking dopaminergic (D2) and alpha-adrenergic receptors in the central nervous system.

  Dosage: Psychosis: start 25-50 mg/day, maintenance 150-250 mg/day. Pain: 12.5 mg 4-6 times daily up to 300-500 mg/day for severe pain.
• +Promethazine Hydrochloride2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Promethazine is a phenothiazine derivative that acts as an antagonist on various receptors, including histamine H1 receptors, muscarinic acetylcholine receptors, and dopamine D2 receptors.

  Dosage: Adults (allergy): 15-150 mg per day in divided doses during meals and at bedtime. Motion sickness (adults/children >8 years): 25 mg, 0.5-1 hour before departure, repeat after 8 hours if necessary. Children >2 years (allergy): 0.2 mg/kg 2-4 times per day.
• +NABILONE2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Synthetic cannabinoid that acts as a weak partial agonist at CB1 and CB2 receptors, mimicking the pharmacological activity of THC.

  Dosage: 2 to 3 times daily, starting 1 to 3 hours before chemotherapy and continued until 48 hours after the cycle.
• +Amitriptyline2 bronnenop voorschrift — vraag je arts
  About the substance

  Tricyclic antidepressant that inhibits the reuptake of norepinephrine and serotonin, and also possesses ion channel blocking effects (sodium, potassium, NMDA) and anticholinergic properties.

  Dosage: Adults (depression): starting dose 25 mg twice daily, gradually increased to a maximum of 150 mg per day.
• +Promethazine2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Promethazine is a phenothiazine derivative that acts as an antagonist on various receptors, including histamine H1 receptors, muscarinic acetylcholine receptors, and dopamine D2 receptors.

  Dosage: Adults (allergy): 15-150 mg per day in divided doses during meals and at bedtime. Motion sickness (adults/children >8 years): 25 mg, 0.5-1 hour before departure, repeat after 8 hours if necessary. Children >2 years (allergy): 0.2 mg/kg 2-4 times per day.
• +Clonazepam2 bronnenop voorschrift — vraag je arts
  About the substance

  Benzodiazepine with anxiolytic, hypnotic-sedative, muscle-relaxant, and anticonvulsant properties; works via positive allosteric modulation of the GABA-A receptor, enhancing inhibitory GABAergic neurotransmission and chloride ion flux.

  Dosage: To be adjusted individually by the physician; often start with a low dose that is gradually increased. Tablets are divisible for dose adjustment.
• +Gabapentin2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Gabapentin is an antiepileptic drug that binds to the α2δ subunit of voltage-gated calcium channels in the central nervous system, thereby modulating neurotransmission.

  Dosage: Starting schedule for adults/adolescents (≥12 years): day 1: 300 mg once daily, day 2: 300 mg twice daily, day 3: 300 mg three times daily. Discontinue by gradually tapering over at least 1 week.

Bron: dis-treat master (BCFI/itreat · EMA · SIDER · FAERS-frequentie). Geen diagnose — dit vervangt geen consult.